Practice Points:
- During TH:
- Achieve peripheral oxygen saturation with the least possible fraction of inspired oxygen (FiO2)
- Minimize ventilation settings if intubated to avoid hypocapnia
- Heat inspired gas to 37 ◦C and ensure 100% relative humidity
- Interpret blood gas values corrected for the actual temperature of the infant
- May use mild sedation to overcome any discomfort related to cooling
- Avoid:
- Hyperventilation and hyperoxemia, as hypocapnia and oxygen radicals can contribute to brain damage
- The use of alkaline buffers, paralytic agents and heavy sedation, since these medications have serious side effects on the brain
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