Monthly Highlights


September 2021:

 
Management of seizures in neonates with neonatal encephalopathy treated with hypothermia.
DeLaGarza-Pineda O, Mailo JA, Boylan G, Chau V, Glass HC, Mathur AM, Shellhaas RA, Soul JS, Wusthoff CJ, Chang T; Newborn Brain Society Guidelines and Publications Committee.
Semin Fetal Neonatal Med. 2021 Sep 15:101279. doi: 10.1016/j.siny.2021.101279. Online ahead of print.
PMID: 34563467 Review.

 
Multi-organ dysfunction scoring in neonatal encephalopathy (MODE Score) and neurodevelopmental outcomes.
Sweetman DU, Strickland T, Isweisi E, Kelly L, Slevin MT, Donoghue V, Meehan J, Boylan G, Murphy JFA, El-Khuffash A, Molloy EJ.
Acta Paediatr. 2021 Sep 16. doi: 10.1111/apa.16111. Online ahead of print.
PMID: 34528287

 
Supporting families in their child’s journey with neonatal encephalopathy and therapeutic hypothermia.
Pilon B, Craig AK, Lemmon ME, Goeller A; Newborn Brain Society Guidelines and Publications Committee.
Semin Fetal Neonatal Med. 2021 Sep 16:101278. doi: 10.1016/j.siny.2021.101278. Online ahead of print.
PMID: 34561175

 
Neonatal stroke enhances interaction of microglia-derived extracellular vesicles with microglial cells.
Lecuyer M, Pathipati P, Faustino J, Vexler ZS.
Neurobiol Dis. 2021 Sep;157:105431. doi: 10.1016/j.nbd.2021.105431. Epub 2021 Jun 19.
PMID: 34153465

 
Changing clinical characteristics of infants treated for hypoxic-ischaemic encephalopathy in England, Wales and Scotland: a population-based study using the National Neonatal Research Database.
Hage L, Jeyakumaran D, Dorling J, Ojha S, Sharkey D, Longford N, Modi N, Battersby C, Gale C.
Arch Dis Child Fetal Neonatal Ed. 2021 Sep;106(5):501-508. doi: 10.1136/archdischild-2020-319685. Epub 2021 Feb 4.
PMID: 33541916

 
[Adherence to hypothermia guidelines in newborns with hypoxic-ischemic encephalopathy].
Vega-Del-Val C, Arnaez J, Caserío S, Gutiérrez EP, Castañón L, Benito M, Garcia-Alix A; Grupo ARAHIP.
An Pediatr (Barc). 2021 Sep 14:S1695-4033(21)00245-9. doi: 10.1016/j.anpedi.2021.07.008. Online ahead of print.
PMID: 34535415 Spanish.

 

A practical guide to publishing a quality improvement paper.
Pearlman SA, Swanson JR. J Perinatol. 2021 Jun;41(6):1454-1458. doi: 10.1038/s41372-020-00902-w. Epub 2021 Jan 4. PMID: 33398057.

 
Project Console: a quality improvement initiative for neonatal abstinence syndrome in a children’s hospital level IV neonatal intensive care unit. Ponder KL, Egesdal C, Kuller J, Joe P. BMJ Open Qual. 2021 May;10(2):e001079. doi: 10.1136/bmjoq-2020-001079. PMID: 33941537; PMCID: PMC8098972.

 
Reducing Opioid Exposure in a Level IV Neonatal Intensive Care Unit. Stetson RC, Smith BN, Sanders NL, Misgen MA, Ferrie LJ, Schuning VS, Schuh AR, Fang JL, Brumbaugh JE. , Pediatr Qual Saf. 2020 Jun 26;5(4):e312. doi: 10.1097/pq9.0000000000000312. PMID: 32766487; PMCID: PMC7339154.

 

August 2021:

 

Prenatal clinical manifestations in individuals with COL4A1/2 variants.
Itai T, Miyatake S, Taguri M, Nozaki F, Ohta M, Osaka H, Morimoto M, Tandou T, Nohara F, Takami Y, Yoshioka F, Shimokawa S, Okuno-Yuguchi J, Motobayashi M, Takei Y, Fukuyama T, Kumada S, Miyata Y, Ogawa C, Maki Y, Togashi N, Ishikura T, Kinoshita M, Mitani Y, Kanemura Y, Omi T, Ando N, Hattori A, Saitoh S, Kitai Y, Hirai S, Arai H, Ishida F, Taniguchi H, Kitabatake Y, Ozono K, Nabatame S, Smigiel R, Kato M, Tanda K, Saito Y, Ishiyama A, Noguchi Y, Miura M, Nakano T, Hirano K, Honda R, Kuki I, Takanashi JI, Takeuchi A, Fukasawa T, Seiwa C, Harada A, Yachi Y, Higashiyama H, Terashima H, Kumagai T, Hada S, Abe Y, Miyagi E, Uchiyama Y, Fujita A, Imagawa E, Azuma Y, Hamanaka K, Koshimizu E, Mitsuhashi S, Mizuguchi T, Takata A, Miyake N, Tsurusaki Y, Doi H, Nakashima M, Saitsu H, Matsumoto N.
J Med Genet. 2021 Aug;58(8):505-513. doi: 10.1136/jmedgenet-2020-106896. Epub 2020 Jul 30.
PMID: 32732225

 

Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh.
Thayyil S, Pant S, Montaldo P, Shukla D, Oliveira V, Ivain P, Bassett P, Swamy R, Mendoza J, Moreno-Morales M, Lally PJ, Benakappa N, Bandiya P, Shivarudhrappa I, Somanna J, Kantharajanna UB, Rajvanshi A, Krishnappa S, Joby PK, Jayaraman K, Chandramohan R, Kamalarathnam CN, Sebastian M, Tamilselvam IA, Rajendran UD, Soundrarajan R, Kumar V, Sudarsanan H, Vadakepat P, Gopalan K, Sundaram M, Seeralar A, Vinayagam P, Sajjid M, Baburaj M, Murugan KD, Sathyanathan BP, Kumaran ES, Mondkar J, Manerkar S, Joshi AR, Dewang K, Bhisikar SM, Kalamdani P, Bichkar V, Patra S, Jiwnani K, Shahidullah M, Moni SC, Jahan I, Mannan MA, Dey SK, Nahar MN, Islam MN, Shabuj KH, Rodrigo R, Sumanasena S, Abayabandara-Herath T, Chathurangika GK, Wanigasinghe J, Sujatha R, Saraswathy S, Rahul A, Radha SJ, Sarojam MK, Krishnan V, Nair MK, Devadas S, Chandriah S, Venkateswaran H, Burgod C, Chandrasekaran M, Atreja G, Muraleedharan P, Herberg JA, Kling Chong WK, Sebire NJ, Pressler R, Ramji S, Shankaran S; HELIX consortium.
Lancet Glob Health. 2021 Sep;9(9):e1273-e1285. doi: 10.1016/S2214-109X(21)00264-3. Epub 2021 Aug 3.
PMID: 34358491 Free PMC article. Clinical Trial.

 

Seizure Control in Neonates Undergoing Screening vs Confirmatory EEG Monitoring.
Wusthoff CJ, Sundaram V, Abend NS, Massey SL, Lemmon ME, Thomas C, McCulloch CE, Chang T, Soul JS, Chu CJ, Rogers EE, Bonifacio SL, Cilio MR, Glass HC, Shellhaas RA; Neonatal Seizure Registry Group.
Neurology. 2021 Aug 10;97(6):e587-e596. doi: 10.1212/WNL.0000000000012293. Epub 2021 Jun 2.
PMID: 34078719 Free PMC article.

 

Identifying Ways to Fix Outcome Disparities among Outborns Needing Therapeutic Hypothermia.
Harbert MJA, Sey R, Arnell K, Rasmussen M.
Am J Perinatol. 2021 Aug;38(S 01):e21-e25. doi: 10.1055/s-0040-1702990. Epub 2020 Mar 2.
PMID: 32120421

 

Hammersmith Infant Neurological Examination for infants born preterm: predicting outcomes other than cerebral palsy.
Romeo DM, Cowan FM, Haataja L, Ricci D, Pede E, Gallini F, Cota F, Brogna C, Vento G, Romeo MG, Mercuri E.
Dev Med Child Neurol. 2021 Aug;63(8):939-946. doi: 10.1111/dmcn.14768. Epub 2020 Dec 18.
PMID: 33336801

 

Early-life epilepsy after acute symptomatic neonatal seizures: A prospective multicenter study.
Shellhaas RA, Wusthoff CJ, Numis AL, Chu CJ, Massey SL, Abend NS, Soul JS, Chang T, Lemmon ME, Thomas C, McNamara NA, Guillet R, Franck LS, Sturza J, McCulloch CE, Glass HC.
Epilepsia. 2021 Aug;62(8):1871-1882. doi: 10.1111/epi.16978. Epub 2021 Jul 2.
PMID: 34212365

 

Parental Enrollment Decision-Making for a Neonatal Clinical Trial.
Weiss EM, Guttmann KF, Olszewski AE, Magnus BE, Li S, Kim SYH, Shah AR, Juul SE, Wu YW, Ahmad KA, Bendel-Stenzel E, Isaza NA, Lampland AL, Mathur AM, Rao R, Riley D, Russell DG, Salih ZNI, Torr CB, Weitkamp JH, Anani UE, Chang T, Dudley J, Flibotte J, Havrilla EM, O’Kane AC, Perez K, Stanley BJ, Shah SK, Wilfond BS.
J Pediatr. 2021 Aug 14:S0022-3476(21)00770-8. doi: 10.1016/j.jpeds.2021.08.014. Online ahead of print.
PMID: 34400207

 

Improving Compliance and Quality of Documentation of Cerebral Function Monitoring in a Neonatal Neurocritical Care Unit.
Goswami I, Chansarn P, Aldana Aguirre J, Taher F, Wilson D, Hahn C, ElShahed A, Lee KS.
Pediatr Qual Saf. 2021 Aug 26;6(5):e461. doi: 10.1097/pq9.0000000000000461. eCollection 2021 Sep-Oct.
PMID: 34476313 Free PMC article.

 

Neonates with mild hypoxic-ischaemic encephalopathy receiving supportive care versus therapeutic hypothermia in California.
Yieh L, Lee H, Lu T, Song A, Gong CL, Wu TW, Friedlich P, Lakshmanan A, Dukhovny D, Hay J.
Arch Dis Child Fetal Neonatal Ed. 2021 Aug 30:fetalneonatal-2021-322250. doi: 10.1136/archdischild-2021-322250. Online ahead of print.
PMID: 34462319

 

July 2021:

 

Children with perinatal stroke are at increased risk for autism spectrum disorder: Prevalence and co-occurring conditions within a clinically followed sample.
Hamner T, Shih E, Ichord R, Krivitzky L.
Clin Neuropsychol. 2021 Jul 24:1-12. doi: 10.1080/13854046.2021.1955150. Online ahead of print.
PMID: 34308766

 

Neonatal Subpial Hemorrhage: Clinical Factors, Neuroimaging, and Outcomes in a Quaternary Care Children’s Center.
Dabrowski AK, Carrasco M, Gatti JR, Barreto ARF, Parkinson C, Robinson S, Tekes A, Sun LR.
Pediatr Neurol. 2021 Jul;120:52-58. doi: 10.1016/j.pediatrneurol.2021.04.011. Epub 2021 Apr 28.
PMID: 34020112

 

High-frequency oscillations recorded with surface EEG in neonates with seizures.
Noorlag L, van ‘t Klooster MA, van Huffelen AC, van Klink NEC, Benders MJNL, de Vries LS, Leijten FSS, Jansen FE, Braun KPJ, Zijlmans M.
Clin Neurophysiol. 2021 Jul;132(7):1452-1461. doi: 10.1016/j.clinph.2021.02.400. Epub 2021 Apr 16.
PMID: 34023627

 

Multichannel EEG abnormalities during the first 6 hours in infants with mild hypoxic-ischaemic encephalopathy.
Garvey AA, Pavel AM, O’Toole JM, Walsh BH, Korotchikova I, Livingstone V, Dempsey EM, Murray DM, Boylan GB.
Pediatr Res. 2021 Jul;90(1):117-124. doi: 10.1038/s41390-021-01412-x. Epub 2021 Apr 20.
PMID: 33879847 Free PMC article.

 

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures.
Glass HC, Soul JS, Chang T, Wusthoff CJ, Chu CJ, Massey SL, Abend NS, Lemmon M, Thomas C, Numis AL, Guillet R, Sturza J, McNamara NA, Rogers EE, Franck LS, McCulloch CE, Shellhaas RA.
JAMA Neurol. 2021 Jul 1;78(7):817-825. doi: 10.1001/jamaneurol.2021.1437.
PMID: 34028496 Free PMC article.

 

Incidental findings on brain MR imaging of asymptomatic term neonates in the Developing Human Connectome Project.
Carney O, Hughes E, Tusor N, Dimitrova R, Arulkumaran S, Baruteau KP, Collado AE, Cordero-Grande L, Chew A, Falconer S, Allsop JM, Rueckert D, Hajnal J, Edwards AD, Rutherford M.
EClinicalMedicine. 2021 Jul 20;38:100984. doi: 10.1016/j.eclinm.2021.100984. eCollection 2021 Aug.
PMID: 34355154 Free PMC article.

 

Predictors of Neurodevelopmental Impairment After Neonatal Bacterial Meningitis.
Haffner DN, Machie M, Hone E, Said RR, Maitre NL.
J Child Neurol. 2021 Oct;36(11):968-973. doi: 10.1177/08830738211026053. Epub 2021 Jul 13.
PMID: 34256644

 

Interobserver Reliability for Identifying Specific Patterns of Placental Injury as Defined by the Amsterdam Classification.
Redline RW, Vik T, Heerema-McKenney A, Jamtoy AH, Ravishankar S, Ton Nu TN, Vogt C, Ng P, Nelson KB, Lydersen S, Oskoui M.
Arch Pathol Lab Med. 2021 Jul 9. doi: 10.5858/arpa.2020-0753-OA. Online ahead of print.
PMID: 34252177

 

Cholesterol metabolism and brain injury in neonatal encephalopathy. Dave AM, Peeples ES.
Pediatr Res. 2021 Jul;90(1):37-44. doi: 10.1038/s41390-020-01218-3. Epub 2020 Oct 26.
PMID: 33106607 Review.

June 2021:

 

Commentary – the late preterm infant: Vulnerable cerebral cortex and large burden of disability.

Volpe JJ. J Neonatal Perinatal Med. 2021 Jun 27. doi: 10.3233/NPM-210803. Online ahead of print.

PMID: 34219675. No abstract available.

 

Erythropoietin monotherapy for neuroprotection after neonatal encephalopathy in low-to-middle income countries: a systematic review and meta-analysis.

Ivain P, Montaldo P, Khan A, Elagovan R, Burgod C, Morales MM, Pant S, Thayyil S. J Perinatol. 2021 Jun 26. doi: 10.1038/s41372-021-01132-4. Online ahead of print.

PMID: 34175900 Review.

 

Imaging the construction of capillary networks in the neonatal mouse brain.

Coelho-Santos V, Berthiaume AA, Ornelas S, Stuhlmann H, Shih AY. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2100866118. doi: 10.1073/pnas.2100866118.

PMID: 34172585

 

Blood gas measures as predictors for neonatal encephalopathy severity.

Sakpichaisakul K, Supapannachart KJ, El-DIb M, Szakmar E, Yang E, Walsh BH, Robinson JN, Cherkerzian S, Volpe JJ, Inder TE. J Perinatol. 2021 Jun 24. doi: 10.1038/s41372-021-01075-w. Online ahead of print.

PMID: 34168288

 

Neonatal presentation of genetic epilepsies: Early differentiation from acute provoked seizures.

Cornet MC, Morabito V, Lederer D, Glass HC, Ferrao Santos S, Numis AL, Ferriero DM, Sands TT, Cilio MR. Epilepsia. 2021 Jun 21. doi: 10.1111/epi.16957. Online ahead of print.

PMID: 34153113

 

Spatial and cell type transcriptional landscape of human cerebellar development.

Aldinger KA, Thomson Z, Phelps IG, Haldipur P, Deng M, Timms AE, Hirano M, Santpere G, Roco C, Rosenberg AB, Lorente-Galdos B, Gulden FO, O’Day D, Overman LM, Lisgo SN, Alexandre P, Sestan N, Doherty D, Dobyns WB, Seelig G, Glass IA, Millen KJ. Nat Neurosci. 2021 Jun 17. doi: 10.1038/s41593-021-00872-y. Online ahead of print.

PMID: 34140698

 

Seizure Control in Neonates Undergoing Screening vs Confirmatory EEG Monitoring.

Wusthoff CJ, Sundaram V, Abend NS, Massey SL, Lemmon ME, Thomas C, McCulloch CE, Chang T, Soul JS, Chu CJ, Rogers EE, Bonifacio SL, Cilio MR, Glass HC, Shellhaas RA; Neonatal Seizure Registry Group. Neurology. 2021 Jun 2:10.1212/WNL.0000000000012293. doi: 10.1212/WNL.0000000000012293. Online ahead of print.

PMID: 34078719

 

Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats.

Lippman-Bell JJ, Handy M, Nieder CG, Getzfread M, Jensen FE. Mol Cell Neurosci. 2021 Jun;113:103629. doi: 10.1016/j.mcn.2021.103629. Epub 2021 May 18.

PMID: 34015497

 

Human umbilical cord mesenchymal stromal cells as an adjunct therapy with therapeutic hypothermia in a piglet model of perinatal asphyxia.

Robertson NJ, Meehan C, Martinello KA, Avdic-Belltheus A, Boggini T, Mutshiya T, Lingam I, Yang Q, Sokolska M, Charalambous X, Bainbridge A, Hristova M, Kramer BW, Golay X, Weil B, Lowdell MW. Cytotherapy. 2021 Jun;23(6):521-535. doi: 10.1016/j.jcyt.2020.10.005. Epub 2020 Nov 28.

PMID: 33262073 Free PMC article.

 

Telemedicine consults to assess neonatal encephalopathy are feasible in the neonatal intensive care unit.

Craig AK, McAllister LM, Evans S, Melendi ME. J Perinatol. 2021 Jun;41(6):1519-1521. doi: 10.1038/s41372-020-00828-3. Epub 2020 Sep 21.

PMID: 32958837 No abstract available.

 

General Knowledge on Safety/Quality:

 

Costs of Neonatal Intensive Care for Canadian Infants with Preterm Birth.

Rios JD, Shah PS, Beltempo M, Louis D, Mukerji A, Premji S, Shah V, Lee SK, Pechlivanoglou P; Canadian Preterm Birth Network Investigators; Canadian Neonatal Network Investigators. J Pediatr. 2021 Feb;229:161-167.e12. doi: 10.1016/j.jpeds.2020.09.045. Epub 2020 Sep 23.

PMID: 32979384.

 

QI:

 

The E-Nurture Project: A Hybrid Virtual Neonatal Follow Up Model for 2021.

Church PT, Banihani R, Watson J, Chen WTN, Ballantyne M, Asztalos E. Children (Basel). 2021 Feb 12;8(2):139. doi: 10.3390/children8020139.

PMID: 33673246; PMCID: PMC7918063.

 

Effects of blood sampling stewardship and erythropoietin administration in extremely low birth weight infants-a quality improvement non-controlled before-and-after retrospective study.

Balasubramanian H, Atyalgade M, Garg B, Srinivasan L, Kabra NS, Khapekar S. Eur J Pediatr. 2021 May;180(5):1617-1626. doi: 10.1007/s00431-020-03925-9. Epub 2021 Jan 19.

PMID: 33464366.

 

May 2021:

 

Racial and Ethnic Disparities in Adverse Perinatal Outcomes at Term.

Parchem JG, Rice MM, Grobman WA, Bailit JL, Wapner RJ, Debbink MP, Thorp JM Jr, Caritis SN, Prasad M, Tita ATN, Saade GR, Sorokin Y, Rouse DJ, Tolosa JE; Eunice Kennedy Shriver National Institute of Child Health Human Development Maternal-Fetal Medicine Units (MFMU) Network. Am J Perinatol. 2021 May 31. doi: 10.1055/s-0041-1730348. Epub ahead of print.

PMID: 34058765.

 

Emerging Ethical Issues Raised by Highly Portable MRI Research in Remote and Resource-Limited International Settings.

Shen FX, Wolf SM, Bhavnani S, Deoni S, Elison JT, Fair D, Garwood M, Gee MS, Geethanath S, Kay K, Lim KO, Lockwood-Estrin G, Luciana M, Peloquin D, Rommelfanger K, Schiess N, Siddiqui K, Torres E, Vaughan JT. Neuroimage. 2021 May 29:118210. doi: 10.1016/j.neuroimage.2021.118210. Epub ahead of print.

PMID: 34062266.

 

Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia-ischemia.

Martinello KA, Meehan C, Avdic-Belltheus A, Lingam I, Mutshiya T, Yang Q, Akin MA, Price D, Sokolska M, Bainbridge A, Hristova M, Tachtsidis I, Tann CJ, Peebles D, Hagberg H, Wolfs TGAM, Klein N, Kramer BW, Fleiss B, Gressens P, Golay X, Robertson NJ.  Pediatr Res. 2021 May 28:1–12. doi: 10.1038/s41390-021-01584-6. Epub ahead of print.

PMID: 34050269; PMCID: PMC8160560.

 

Outcomes of neonatal hypoxic-ischaemic encephalopathy in centres with and without active therapeutic hypothermia: a nationwide propensity score-matched analysis.

Shipley L, Mistry A, Sharkey D.  Arch Dis Child Fetal Neonatal Ed. 2021 May 27:fetalneonatal-2020-320966. doi: 10.1136/archdischild-2020-320966. Epub ahead of print.

PMID: 34045283.

 

Mechanical Ventilation, Partial Pressure of Carbon Dioxide, Increased Fraction of Inspired Oxygen and the Increased Risk for Adverse Short-Term Outcomes in Cooled Asphyxiated Newborns.

Giannakis S, Ruhfus M, Markus M, Stein A, Hoehn T, Felderhoff-Mueser U, Sabir H. Children (Basel). 2021 May 21;8(6):430. doi: 10.3390/children8060430.

PMID: 34063852.

 

Venovenous versus venoarterial extracorporeal membrane oxygenation among infants with hypoxic-ischemic encephalopathy: is there a difference in outcome?

Agarwal P, Natarajan G, Sullivan K, Rao R, Rintoul N, Zaniletti I, Keene S, Mietzsch U, Massaro AN, Billimoria Z, Dirnberger D, Hamrick S, Seabrook RB, Weems MF, Cleary JP, Gray BW, DiGeronimo R; Children’s Hospital Neonatal Consortium (CHNC) ECMO and HIE focus groups.  J Perinatol. 2021 May 19. doi: 10.1038/s41372-021-01089-4. Epub ahead of print.

PMID: 34012056.

 

Duration of mechanical ventilation is more critical for brain growth than postnatal hydrocortisone in extremely preterm infants.

Rousseau C, Guichard M, Saliba E, Morel B, Favrais G. Eur J Pediatr. 2021 May 16. doi: 10.1007/s00431-021-04113-z. Epub ahead of print.

PMID: 33993400.

 

Early Determination of Prognosis in Neonatal Moderate or Severe Hypoxic-Ischemic Encephalopathy.

Ambalavanan N, Shankaran S, Laptook AR, Carper BA, Das A, Carlo WA, Cotten CM, Duncan AF, Higgins RD; EUNICE KENNEDY SHRIVER NICHD NEONATAL RESEARCH NETWORK. Pediatrics. 2021 Jun;147(6):e2020048678. doi: 10.1542/peds.2020-048678. Epub 2021 May 13.

PMID: 33986149; PMCID: PMC8168606.

 

Short-term outcomes in infants with mild neonatal encephalopathy: a retrospective, observational study.

Aoki Y, Kono T, Enokizono M, Okazaki K. BMC Pediatr. 2021 May 7;21(1):224. doi: 10.1186/s12887-021-02688-y.

PMID: 33962618; PMCID: PMC8103637.

 

Interobserver Reliability of an MR Imaging Scoring System in Infants with Hypoxic-Ischemic Encephalopathy.

Szakmar E, Meunier H, El-Dib M, Yang E, Inder TE. AJNR Am J Neuroradiol. 2021 May;42(5):969-974. doi: 10.3174/ajnr.A7048. Epub 2021 Mar 25.

PMID: 33766829; PMCID: PMC8115372.

General Knowledge on Safety/Quality:

 

Becoming an Antiracist Neonatal Community.

Vance AJ, Bell T. Adv Neonatal Care. 2021 Feb 1;21(1):9-15. doi: 10.1097/ANC.0000000000000829.

PMID: 33497141.

QI:

 

Development of a small baby unit to improve outcomes for the extremely premature infant.

Fathi O, Nelin LD, Shepherd EG, Reber KM. J Perinatol. 2021 Mar 12:1–8. doi: 10.1038/s41372-021-00984-0. Epub ahead of print.

PMID: 33712714; PMCID: PMC7952830.

 

Continued improvement in morbidity reduction in extremely premature infants.

Kaempf J, Morris M, Steffen E, Wang L, Dunn M. Arch Dis Child Fetal Neonatal Ed. 2021 May;106(3):265-270. doi: 10.1136/archdischild-2020-319961. Epub 2020 Oct 27.

PMID: 33109606.

 

April 2021:

 

Multichannel EEG abnormalities during the first 6 hours in infants with mild hypoxic-ischaemic encephalopathy.

Garvey AA, Pavel AM, O’Toole JM, Walsh BH, Korotchikova I, Livingstone V, Dempsey EM, Murray DM, Boylan GB. Pediatr Res. 2021 Apr 20. doi: 10.1038/s41390-021-01412-x. Online ahead of print.

PMID: 33879847

 

Feeding during neonatal therapeutic hypothermia, assessed using routinely collected National Neonatal Research Database data: a retrospective, UK population-based cohort study.

Gale C, Longford NT, Jeyakumaran D, Ougham K, Battersby C, Ojha S, Dorling J. Lancet Child Adolesc Health. 2021 Apr 20:S2352-4642(21)00026-2. doi: 10.1016/S2352-4642(21)00026-2. Online ahead of print.

PMID: 33891879

 

Mortality, neurodevelopmental impairments, and economic outcomes after invasive group B streptococcal disease in early infancy in Denmark and the Netherlands: a national matched cohort study.

Horváth-Puhó E, van Kassel MN, Gonçalves BP, de Gier B, Procter SR, Paul P, van der Ende A, Søgaard KK, Hahné SJM, Chandna J, Schrag SJ, van de Beek D, Jit M, Sørensen HT, Bijlsma MW, Lawn JE. Lancet Child Adolesc Health. 2021 Apr 21:S2352

4642(21)00022-5. doi: 10.1016/S2352-4642(21)00022-5. Online ahead of print.

PMID: 33894156

 

Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity Among Preterm Infants.

jöbom U, Hellström W, Löfqvist C, Nilsson AK, Holmström G, Pupp IH, Ley D, Blennow K, Zetterberg H, Sävman K, Hellström A. JAMA Netw Open. 2021 Apr 1;4(4):e214138. doi: 10.1001/jamanetworkopen.2021.4138.

PMID: 33797551 Free PMC article.

 

Association between early cerebral oxygenation and neurodevelopmental impairment or death in premature infants.

Katheria AC, Stout J, Morales AL, Poeltler D, Rich WD, Steen J, Nuzzo S, Finer N. J Perinatol. 2021 Apr;41(4):743-748. doi: 10.1038/s41372-021-00942-w. Epub 2021 Feb 15.

PMID: 33589727 Free PMC article.

 

QIPS Knowledge:

 

Improving the quality of quality metrics in neonatology.

Hagadorn JI, Johnson KR, Hill D, Sink DW. Semin Perinatol. 2020 Jun;44(4):151244. doi: 10.1016/j.semperi.2020.151244. Epub 2020 Mar 13.

PMID: 32248956

 

QI Studies:

 

Optimizing practice guidelines through incorporating patient and family values and preferences.

Mitra S, Dorling J, Johnston BC. Semin Fetal Neonatal Med. 2021 Feb;26(1):101194. doi: 10.1016/j.siny.2021.101194. Epub 2021 Jan 18.

PMID: 33504465

 

Network Implementation of Guideline for Early Detection Decreases Age at Cerebral Palsy Diagnosis.

Maitre NL, Burton VJ, Duncan AF, Iyer S, Ostrander B, Winter S, Ayala L, Burkhardt S, Gerner G, Getachew R, Jiang K, Lesher L, Perez CM, Moore-Clingenpeel M, Lam R, Lewandowski DJ, Byrne R. Pediatrics. 2020 May;145(5):e20192126. doi:

10.1542/peds.2019-2126. Epub 2020 Apr 8. PMID: 32269135; PMCID: PMC7193973.

 

March 2021:

 

The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures.

Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM.

Epilepsia. 2021 Mar;62(3):615-628. doi: 10.1111/epi.16815. Epub 2021 Feb 1.

PMID: 33522601

 

Parent mental health and neurodevelopmental outcomes of children hospitalized in the neonatal intensive care unit.

Erdei C, Liu CH, Machie M, Church PT, Heyne R.

Early Hum Dev. 2021 Mar;154:105278. doi: 10.1016/j.earlhumdev.2020.105278. Epub 2020 Nov 16.

PMID: 33221031

 

Trends in the incidence and management of hypoxic-ischaemic encephalopathy in the therapeutic hypothermia era: a national population study.

Shipley L, Gale C, Sharkey D.

Arch Dis Child Fetal Neonatal Ed. 2021 Mar 8:fetalneonatal-2020-320902. doi: 10.1136/archdischild-2020-320902. Online ahead of print.

PMID: 33685945

 

Interobserver Reliability of a MR Imaging Scoring System in Infants with Hypoxic-Ischemic Encephalopathy.

Szakmar E, Meunier H, El-Dib M, Yang E, Inder TE.

AJNR Am J Neuroradiol. 2021 Mar 25. doi: 10.3174/ajnr.A7048. Online ahead of print.

PMID: 33766829

 

A connectome-based approach to assess motor outcome after neonatal arterial ischemic stroke.

Al Harrach M, Pretzel P, Groeschel S, Rousseau F, Dhollander T, Hertz-Pannier L, Lefevre J, Chabrier S, Dinomais M; AVCnn study group.

Ann Clin Transl Neurol. 2021 Mar 30. doi: 10.1002/acn3.51292. Online ahead of print.

PMID: 33787079

 

QI:

 

Measurement for quality improvement: using data to drive change.

Gupta M, Kaplan HC.

Journal of Perinatology 40,962-971. 2020.

PMID: 31915369

 

Development of a small baby unit to improve outcomes of extremely premature infants.

Fathi O, Nelin LD, Sheperd EG, Reber KM.

Journal of Perinatology. 2021.

https://doi.org/10.1038/s41372-021-00984-0.

 

February 2021:

 

Moderately and Late Preterm Infants: Short- and Long-Term Outcomes From a Registry-Based Cohort.

Smyrni N, Koutsaki M, Petra M, Nikaina E, Gontika M, Strataki H, Davora F, Bouza H, Damianos G, Skouteli H, Mastroyianni S, Dalivigka Z, Dinopoulos A, Tzaki M, Papavasiliou A.

Front Neurol. 2021 Feb 12;12:628066. doi: 10.3389/fneur.2021.628066. eCollection 2021.

PMID: 33643206 Free PMC article.

 

Effects of therapeutic hypothermia on death among asphyxiated neonates with hypoxic-ischemic encephalopathy: A systematic review and meta-analysis of randomized control trials.

Abate BB, Bimerew M, Gebremichael B, Mengesha Kassie A, Kassaw M, Gebremeskel T, Bayih WA.

PLoS One. 2021 Feb 25;16(2):e0247229. doi: 10.1371/journal.pone.0247229. eCollection 2021.

PMID: 33630892 Free PMC article.

 

Therapeutic potential of stem cells for preterm infant brain damage: Can we move from the heterogeneity of preclinical and clinical studies to established therapeutics?

Passera S, Boccazzi M, Bokobza C, Faivre V, Mosca F, Van Steenwinckel J, Fumagalli M, Gressens P, Fleiss B.

Biochem Pharmacol. 2021 Feb 8;186:114461. doi: 10.1016/j.bcp.2021.114461. Online ahead of print.

PMID: 33571501 Review.

 

Prevalence, Risk Factors, and Impact of Preoperative Seizures in Neonates With Congenital Heart Disease.

Pittet MP, Marini D, Ly L, Au-Young SH, Chau V, Seed M, Miller SP, Hahn CD.

J Clin Neurophysiol. 2021 Feb 4. doi: 10.1097/WNP.0000000000000825. Online ahead of print.

PMID: 33560701

 

Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates. 

Wang Y, Lafon PA, Salvador-Prince L, Gines AR, Trousse F, Torrent J, Prevostel C, Crozet C, Liu J, Perrier V.

Environ Res. 2021 Feb 4;195:110829. doi: 10.1016/j.envres.2021.110829. Online ahead of print.

PMID: 33548298

 

Monogenic Causes of Apparently Idiopathic Perinatal Intracranial Hemorrhage. 

Hausman-Kedem M, Malinger G, Modai S, Kushner SA, Shiran SI, Ben-Sira L, Roth J, Constantini S, Fattal-Valevski A, Ben-Shachar S.

Ann Neurol. 2021 Feb 2. doi: 10.1002/ana.26033. Online ahead of print.

PMID: 33527515

 

The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures.

Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM.

Epilepsia. 2021 Mar;62(3):615-628. doi: 10.1111/epi.16815. Epub 2021 Feb 1.

PMID: 33522601

 

Neuroprotective role of lactate in rat neonatal hypoxia-ischemia. 

Roumes H, Dumont U, Sanchez S, Mazuel L, Blanc J, Raffard G, Chateil JF, Pellerin L, Bouzier-Sore AK.

J Cereb Blood Flow Metab. 2021 Feb;41(2):342-358. doi: 10.1177/0271678X20908355. Epub 2020 Mar 24.

PMID: 32208801 Free PMC article.

 

A Pilot Randomized, Controlled, Double-Blind Trial of Bumetanide to Treat Neonatal Seizures.

Soul JS, Bergin AM, Stopp C, Hayes B, Singh A, Fortuno CR, O’Reilly D, Krishnamoorthy K, Jensen FE, Rofeberg V, Dong M, Vinks AA, Wypij D, Staley KJ; Boston Bumetanide Trial Group.

Ann Neurol. 2021 Feb;89(2):327-340. doi: 10.1002/ana.25959. Epub 2020 Dec 3.

PMID: 33201535 Clinical Trial.

 

Drug delivery platforms for neonatal brain injury. 

Narayanamurthy R, Yang JJ, Yager JY, Unsworth LD.

J Control Release. 2021 Feb 10;330:765-787. doi: 10.1016/j.jconrel.2020.12.056. Epub 2021 Jan 6.

PMID: 33417984 Review.



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